MESENCHYMAL STROMAL CELL-DERIVED EXTRACELLULAR VESICLES REDUCE LUNG INFLAMMATION AND DAMAGE IN NONCLINICAL ACUTE LUNG INJURY: IMPLICATIONS FOR COVID-19.

Mesenchymal stem cell derived extracellular vesicles (MSC-EVs) are bioactive particles that evoke beneficial responses in recipient cells.We identified a role for MSC-EV in immune modulation and cellular salvage in a model of SARS-CoV-2 induced acute lung injury (ALI) using pulmonary epithelial cells and exposure to 510 cytokines or the SARS-CoV-2

We utilize a standard competition-colonization metapopulation model in order to study the evolutionary assembly of species.Based on earlier work showing how models assuming strict competitive hierarchies will likely lead to runaway evolution and self-extinction for all species, we adopt a continuous competition function that allows for levels of un

A fire suppression model was developed for forested winter range of the Beverly and Qamanirjuaq (formerly Kaminuriak) herds of barren-ground caribou (Rangifer tarandus groenlandicus) in north-central Canada.The model is a balance between total protection, as voiced by some aboriginal people, and a let-burn policy for natural fires advocated by some

Ultra-high-performance concrete (UHPC) exhibits significantly higher tensile strength compared to normal concrete (NC).In this paper, the application of UHPC to the precast base plate of composite slabs was proposed, leading to the development of a reinforced truss UHPC-NC composite slab.This approach effectively enhanced the crack resistance of th

Larvae of Rhipsideigma raffrayi are described in detail and those of Distocupes varians are re-examined.Their morphological structures are evaluated with respect to their functional and phylogenetic significance.Larvae of Rhipsideigma are wood-borers with a straight body and a wedge-shaped head capsule.Most of their apomorphic features are correlat